Margarita A. Sazonova
Russian Cardiology Research and Production Complex, Russia
Title: Investigation of Blood Cell Mitochondrial Genome Mutations in Symptomless Atherosclerosis among Women
Biography
Biography: Margarita A. Sazonova
Abstract
Nowadays atherosclerosis is one of the most common diseases. It is a basis for the majority of cardiovascular pathologies. The aim of the present study was a detection of mitochondrial genome mutations associated with symptomless atherosclerotic lesions of carotid arteries in women. Three atherogenic mutations (C3256T, G14709A and G12315A) and two antiatherogenic ones (G13513A and G14846A), which are associated with symptomless (preclinical) atherosclerosis in women, were found.